There is absolutely no strategy to win on ClixGrid. Its sheer luck, nothing else.
Nothing will increase your odds (clicking here, clicking there, make this pattern, clicking at the same time daily, spreading out your clicks across the day, upgrading, etc.) because it's random like rolling a dice. The odds of winning are about 1 in 400. You may win twice in the same day or none in several days, it's totally random.
It doesn't matter where you click in the grid, for how long you have been a member, how big is your downline, how long you have been playing, nothing really, it's just sheer luck.
The odds of 1 in 400 actually means that for every 400 clicks on the Grid globally, someone will win a prize.
However it does not necessarily mean that you will win on every 400th click you personally make. You may be lucky to win 2 times in a row or nothing for 2000 clicks!
Here are a couple of posts from the Admin regarding this.
1. *NEW* ClixGrid Changes | ClixSense Forum
2. ClixGrid Optimizations and Bonus Clicks | ClixSense Forum